Question: 8 You Identify A Disease In The Epidermal Cells Of Mice In Which Gene A Is Not Transcribed. Further Analyses Reveal That The Sequence Of Gene A Including All Regulatory Sequences Such As Enhancers, Promoters Splicing Junctions Etc. In Affected And Normal Mice Are Identical. Chose The Most Likely Option, From The Choices Below That Could Explain Why …

8 You identify a disease in the epidermal cells of mice in which Gene A is not transcribed. Further analyses reveal that the sequence of Gene A including all regulatory sequences such as enhancers, promoters splicing junctions etc. in affected and normal mice are identical. Chose the most likely option, from the choices below that could explain why Gene A is not transcribed in the epidermal cells of the affected mice. A Mature mRNA corresponding to Gene A lacks the 5 methyl Cap B Epidermal cells of affected mice lack the transcription activators required for Gene A transcription с The Ribosome binding site in mature mRNA transcript corresponding to Gene Ais missing D The mature mRNA corresponding to Gene A lacks a polyA tail E The start codon of the gene is missing